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Ionization constants and pH values at the isoelectric point of α-amino acis in water at 25ºC |
| pKa Values |
| Amino Acid |
carboxyl group(-COOH) |
ammonium ion(-NH3+) |
Side Chain |
Isoelectric point pI |
| Ala |
2.35 |
9.87 |
- |
6.11 |
| Gly |
2.35 |
9.78 |
- |
6.06 |
| Arg |
2.01 |
9.04 |
12.48 |
10.76 |
| Asp |
2.10 |
9.82 |
3.86 |
2.98 |
| Glu |
2.10 |
9.47 |
4.07 |
3.08 |
| His |
1.77 |
9.18 |
6.10 |
7.64 |
| Asp |
2.10 |
9.82 |
3.86 |
2.98 |
| Lys |
2.18 |
8.95 |
10.53 |
9.47 |
| Tyr |
2.20 |
9.11 |
10.07 |
5.63 |
| Cys |
1.04 |
2.05 |
8.0, 10.25 |
5.02 |
| Taken from Pethig p.73 |
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